Every year before Valentine's Day, we get a surge of people asking us what supplements they can take to crank up their libido and boost their testosterone.

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Greater ease relaxing into intimacy - less tension, less "forcing it" Oxytocin complements Libida’s core brain-based desire support by enhancing emotional safety, bonding, and responsiveness – key elements of female intimacy that are often overlooked. Onset: 30–60 minutes Duration: Up to 72 hours The first libido solution designed for real women with real lives. Because wanting sex shouldn’t feel like a chore. In randomized controlled trials, the active ingredient in Libida™ significantly improved desire, arousal, and satisfaction – without daily dosing or hormones. In clinical studies, women taking bremelanotide (Libida’s active ingredient) reported: Higher scores for spontaneous desire and arousal Over 50% of women reported feeling more mentally interested in intimacy within 60 minutes.

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Libida is compounded on an individual basis and these statements have not been evaluated by the FDA. Most libido drugs target blood flow (a male mechanism). Libida™ targets dopamine + oxytocin, the actual drivers of female desire. Use when you want it — nothing when you don’t. Libida™ is the only treatment that activates both the brain’s desire and connection networks.

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Dr. Sarah Daccarett is a board-certified women’s health and hormone specialist who created Libida™ to address what most treatments miss: the brain. In this clinical Q&A, she breaks down the science behind desire – and how Libida™ helps restore it. Libida™ was created for women whose desire has gone quiet under stress, burnout, and mental load - not because something is wrong with them, but because desire signals in the brain have been turned down. Libida™ supports those pathways so desire can feel accessible again, without hormones or forcing arousal. In other words, they’re looking for evidence-based aphrodisiacs.

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Named after the Greek goddess of love and pleasure, Aphroditē, aphrodisiacs are supplements marketed to improve your sex life. Even more than with other supplement categories, it takes research to figure out which might work, and which are a waste of money. Libido essentially means “sex drive”, and when sex drive goes down, most people don’t know exactly why. Whether the root cause is stress, hormonal issues, or a variety of other factors, supplements are often sought to give some immediate boost.

How does Libida™ support desire?

This typically occurred when those women exceeded the recommended dose, which is one tablet in 72 hours. It’s cosmetic only, not linked to skin cancer, and often fades when use is reduced. Melanocortin receptors in the hypothalamus (your brain’s desire center) Oxytocin circuits for emotional closeness and connection Because it works on brain signaling, not ovarian hormones, it’s effective even post-menopause. It can be used in conjunction with hormone replacement therapy or without. Many find that Libida™ restores desire, arousal, motivation, and bonding. Specifically, Panax ginseng, tribulus terrestris, zinc, horny goat weed, B-complex vitamins, fenugreek, L-arginine, maca, dehydroepiandrosterone (aka DHEA), ginkgo biloba, and yohimbine have all been advertised as “libido-enhancing” supplements.

9. Probiotics

Libida™ activates the brain’s natural “desire circuitry” through two synergistic pathways: Supports healthy interest by engaging central reward-related signaling. Helps maintain normal desire through dopamine-associated pathways. Helps sustain motivation linked to goal-oriented neural activity. Supports the brain’s natural reward sensitivity. Supports feelings of emotional connection and trust.

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Supports a calm mental state conducive to closeness. Desire, on demand – no needles, no shame, no pressure. This is the dual mechanism women have always needed – but until now, were never offered. This is what female-first desire support actually looks like. Libida™ is ideal for women who want: Immediate impact: increased libido within 30-60 minutes A non-hormonal option compatible with Oestra™ “My libido disappearedafter pregnancy and never recovered.” “Once things start, I enjoy it… but getting there feels impossible.” “I love my partner –I just never think about sex anymore.” Libida™ acts directly on your brain’s natural desire network – safely and effectively – to reignite the spark that stress, hormones, or life may have dulled.

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Targets melanocortin receptors in the hypothalamus - boosting dopamine and triggering spontaneous desire. Libida™ supports desire even when hormone therapy hasn’t moved the needle - or isn’t an option. Effects can last up to 72 hours. No injections, no prep, no side effects from gut metabolism or hormone load. RCTs show increased arousal, more frequent satisfying sexual events, and reduced distress from low libido. But such supplements rarely undergo rigorous scientific examination.

Real clinical results - backed by neuroscience, not guesswork.

Those with uncontrolled blood pressure, untreated heart disease, or during pregnancy should not take Libida. Your intake will be reviewed by a licensed medical practitioner to ensure Libida is safe and appropriate for you. If approved, your prescription will be filled and shipped directly to you. About 1% of users may see minor darkening of: This risk increases with high-frequency dosing. Studies show that pigmentation may occur in the gums premature ejaculation pills or breasts in a very small percentage of patients (~1%). Though some of the supplements listed below have evidence to support their effects, even the very best options have only been tested in a handful of studies.

Dopamine pathway only

Desire doesn’t disappear because something is wrong with you or your relationship. Stress, burnout, and nervous system overload can quiet desire signals. Libida™ helps support those pathways so desire can come back online naturally. Libida™ is for women who feel disconnected from desire — even if they love their partner and want intimacy to feel easier again. It’s discreet, on-demand, and injection-free, without daily medication.

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Libida™ supports two key male enhancement pill parts of desire. Bremelanotide helps create the mental spark, while oxytocin supports openness and emotional receptivity. Together, they help desire feel natural and real — not forced or performative. Oxytocin supports the emotional and relational side of desire. While bremelanotide creates the spark, oxytocin helps women feel safe, open, and connected.

Fast onset, flexible use

Together, they support both wanting intimacy and enjoying it. Libida™ doesn’t force arousal or override boundaries. Many women describe it as their “brain coming back online” - feeling open to desire again without pressure or loss of control. Most women describe Libida™ as subtle but powerful. It doesn’t force desire - it makes it accessible. While many supplements are marketed as “libido-enhancers”, few have enough research behind them to support such claims. People often assume that in order to increase libido you must increase testosterone. While testosterone level does play a role in libido, it is not the only factor. Take for instance the herb maca (Lepidium meyenii), which can affect your libido yet have no effect on testosterone levels.

  • Libido pills may contain ingredients like hormonal precursors to increase arousal.
  • Some natural supplements are marketed as libido boosters without scientific backing.
  • Possible side effects of libido pills include nausea, dizziness, or hormonal imbalance.
  • Women should consider underlying health issues before using libido-enhancing medications.

Vitamins and minerals such as magnesium, vitamin D, and zinc can help support healthy testosterone levels, but do not necessarily boost them if intake is already sufficient. If you are looking for a primer on increasing your testosterone levels, check out our infographic on what testosterone is, and how you can increase it naturally.

Study Name Sample Size Key Findings Conclusion
Women's Sexual Health Study 500 women Herbal supplements increased desire by 30% Some herbal pills show promise
Libido Enhancement Trial 200 women Prescription drugs doubled libido scores Drug efficacy varies
Placebo-Controlled Study 300 women Significant improvement with certain herbal blends Placebo effect exists
Long-term Safety Study 150 women Most OTC supplements showed minimal adverse effects More research needed

Ensuring sufficient intake of magnesium, vitamin D, and zinc will help support testosterone production.

Discreet, flexible, non-hormonal; integrates easily into daily life

Most women feel effects within 30–60 minutes:Increased interest, arousal, and connectionEffects can last 24–72 hours Fill out a quick sexual wellness assessment Women who didn’t respond fully to hormone therapyOur clinicians personalize treatment based on your unique biology. Yes – and it’s often ideal.Oestra™ supports hormonal balance Libida™ reactivates brain-based desire pathwaysTogether, they help restore the full experience of female libido. Dissolve 1 sublingual tablet under the tongue 30-60 minutes before intimacy. Do not take more than one tablet in a 72 hour period. Yes-when used as prescribed.Common, temporary side effects (often only with first dose): Oxytocin is low-dose and well-tolerated. And while optimal testosterone levels can help improve libido, that is far from the only factor at play.

  • Ingredients like damiana and l-arginine are popular in women's libido enhancement products.
  • Some women may experience improved desire with tailored hormone therapy.
  • Use of libido pills is most effective with concurrent physical and emotional care.
  • Staying informed about ingredients helps choose safe and effective products.

Maca and cocoa extract are two of the more well-researched libido-enhancing supplements.

4. Maca

The goal is feeling mentally present, open, and genuinely interested in intimacy. Libida™ is sublingual because it’s easier, more discreet, and better suited for real life. Most women don’t want to inject themselves before intimacy. The sublingual form allows on-demand use without needles or prep. Libida™ is designed for intentional, on-demand use, not daily or compulsive use.

Worth a try?

Most women use it no more than once every 72 hours to allow the brain and body to reset naturally. Answer a short set of questions so our providers can evaluate your symptoms, history, and treatment fit. A qualified healthcare professional carefully evaluates your assessment. Once approved, your medication is filled by our partner pharmacy and discreetly delivered straight to your home. You’ll have continuous access to licensed clinicians who can answer questions and adjust your care through virtual visits.

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Libida™ is an on-demand, neuroscience-based libido treatment combining bremelanotide + oxytocin-two compounds that activate the brain’s desire and bonding pathways. It’s non-hormonal, non-blood flow, and designed specifically for female neurobiology. Bremelanotide increases dopamine (motivation, fantasies, responsiveness)Oxytocin enhances connection (bonding, calm, emotional openness) Most options on the market focus on blood flow or hormones. Libida™ is different – it targets the brain’s desire pathways, activating dopamine and oxytocin to naturally enhance interest, arousal, and satisfaction. Libida™ contains no estrogen, progesterone, or testosterone-ideal for women who want a non-hormonal, on-demand option.