Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Abnormally shaped penis, including a curved penis and birth defects or Crowded disc or low cup to disc ratio in the eye (an eye disorder) or Hyperlipidemia (high fats in the blood) or Multiple myeloma (cancer of the blood) or Non-arteritic anterior ischemic optic neuropathy (NAION; serious eye condition), history of or Smoking—May increase the chance for a serious side effect in the eye called NAION.
Access through your organization
You may report side effects to FDA at 1-800-FDA-1088. Keep out of the reach of children and pets. Store between 15 and 30 degrees C (59 and 86 degrees F). Get rid of any unused medication after the expiration date. To get rid of medications that are no longer needed or have expired: Take the medication to a medication take-back program.
Does vardenafil interact with foods or drinks?
Check with your pharmacy or law enforcement to find a location. If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance.
More common
Seal the mixture in a bag or container. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Sign up for our Health Essentials emails for expert guidance on nutrition, fitness, sleep, skin care and more. Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals. Blood vessel problems (eg, aortic stenosis, idiopathic subaortic stenosis) or Heart attack (within the last 6 months) or Retinitis pigmentosa (an inherited eye disorder) or Stroke, history of—Should not be used in patients with these conditions.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Levitra Professional | 20mg | 270 + 6 Pills | 738.98€ 703.79€ | |
| Levitra Generic | 20mg | 10 Pills | 31.49€ 29.99€ | |
| Levitra Professional | 20mg | 60 + 2 Pills | 223.11€ 212.49€ | |
| Viagra Generic | 50mg | 180 + 8 Pills | 158.82€ 151.26€ | |
| Viagra Generic | 25mg | 180 + 6 Pills | 154.93€ 147.55€ | |
| Kamagra Gold | 50 mg | 360 + 6 Pills | 713.95€ 679.95€ | |
| Levitra Generic | 60mg | 360 + 10 Pills | 906.69€ 863.51€ | |
| Cialis Generic | 60mg | 30 + 2 Pills | 85.33€ 81.27€ | |
| Levitra Generic | 10mg | 30 + 4 Pills | 62.39€ 59.42€ | |
| Cialis Black | 80mg | 90 + 6 Pills | 207.88€ 197.98€ | |
| Apcalis SX Oral Jelly | 20mg | 120 + 13 Sachets | 280.38€ 267.03€ | |
| Cialis Soft Tabs | 20mg | 120 + 6 Pills | 248.64€ 236.80€ | |
| Viagra Generic | 150mg | 90 + 6 Pills | 147.18€ 140.17€ | |
| Levitra Original | 20mg | 120 + 8 Pills | 528.19€ 503.04€ | |
| Cialis Original | 20mg | 12 Pills | 78.32€ 74.59€ |
Stomach ulcers—Chance of problems occurring may be increased.
How should this medicine be used?
In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. It is not known if the medicine is safe for use in these patients.
Key takeaways:
ED is the inability to achieve and sustain an erection suitable for sexual intercourse. This medication works by increasing blood flow to your penis, which helps you maintain an erection. Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services.
Other Medical Problems
VARDENAFIL (var DEN a fil) treats erectile dysfunction (ED). It works by increasing blood flow to the penis, which helps to maintain an erection. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. They need to know if you have any of these conditions: Eye or vision problems, including a rare inherited eye disease called retinitis pigmentosa Heart disease, angina, a history of heart attack, irregular heart beats, or other heart problems History of blood diseases, such as sickle cell anemia or leukemia An unusual or allergic reaction to vardenafil, other medications, foods, dyes, or preservatives Take this medication by mouth with water. Take it as directed on the prescription label.
What do I need to tell my doctor BEFORE I take this drug?
The dose is usually taken 1 hour before sexual activity. You should not take this dose more than once per day. You can take it with or without food. If it upsets your stomach, take it with food. Talk to your care team about the use of this medication in children. Fructose intolerance—The Staxyn® disintegrating tablet contains sorbitol, which can make this condition worse. QT prolongation (rare heart condition), or history of—Use with caution.
5.12 Phenylketonurics
Vardenafil is used to treat men with erectile dysfunction (sexual impotence). It belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The penis is one of the areas where this enzyme works. Erectile dysfunction is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection.
What is this drug used for?
When a man is sexually stimulated, his body's normal response is to increase blood flow to his penis to produce an erection. By controlling the enzyme, avanafil helps to maintain an erection after the penis is stroked by increasing blood flow to the penis. Without physical action to the penis, such as that occurring during sexual intercourse, avanafil will not work to cause an erection. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: In deciding tadapox tablets to use a medicine, the risks of taking the medicine must be weighed against the good it will do.
How long before sex should I take vardenafil?
This is a decision you and your doctor will make. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Vardenafil is not indicated for use in children. The effects may be increased because of slower removal of the medicine from the body.
5.4 Effects on the Eye
Safety and efficacy have not been established. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of vardenafil in the elderly. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. Phenylketonuria (PKU)—The Staxyn® disintegrating tablet contains aspartame, which can make this condition worse. Use this medicine exactly as directed by your doctor.
What It Contains
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. NOTE: This medicine is only for you. Do not share this medicine with others. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs.
What are some things I need to know or do while I take this drug?
Some items may interact with your medicine. If you notice any changes in your vision while taking this medication, call your care team as soon as possible. Stop using this medication and call your care team right away if you have a loss of sight in one or both eyes. Contact your care team right away if the erection lasts longer than 4 hours or if it becomes painful. This may be a sign of serious problem and must be treated right away to prevent permanent damage.
Testosterone Pellets
If you experience symptoms of nausea, dizziness, chest pain or arm pain upon initiation of sexual activity after taking this medication, you should refrain from further activity and call your care team as soon as possible. Drinking alcohol with this medication can increase the risk of side effects. Using this medication does not protect you or your partner against HIV or other sexually transmitted infections (STIs). Side effects that you should report to your care team as soon as possible: Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat Heart attack—pain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision Stroke—sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision Sudden vision loss in one or both eyes Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome): This list may not describe all possible side effects. Call your doctor for medical advice about side effects. Do not use more of it and do not use it more often than your doctor ordered.
- The recommended dose varies but often is 10 mg.
- Vardenafil should not be used more than once daily.
- Alcohol consumption may reduce its effectiveness.
- Consult a doctor before starting vardenafil.
If you use too much, the chance of having unwanted effects is increased. This medicine should come with a patient information leaflet.
- Vardenafil may cause nasal congestion or upset stomach.
- Use caution when operating machinery after dosing.
- It is not a cure but helps manage erectile dysfunction symptoms.
- Regular medical checkups are recommended during use.
Ask your doctor or pharmacist if you have any questions.
- Vardenafil can cause dizziness or vision changes.
- It is contraindicated if you have severe heart conditions.
- Food, especially high-fat meals, can delay effects.
- Always follow the prescribed dosage instructions.
You may take this medicine with or without food.
- Vardenafil is a selective inhibitor of PDE5 enzyme.
- It is classified as a prescription medication.
- Online purchases should be approached with caution.
- Always disclose your health history to your doctor.
This medicine usually begins to work within 60 minutes after taking it and stimulation of the penis is required. If you have any questions about the use of vardenafil, talk to your doctor.
| Parameter | Value | Notes |
|---|---|---|
| Absorption Time | 30-60 minutes | Peak plasma concentration reached during this time |
| Half-life | 4-5 hours | Duration of drug activity |
| Bioavailability | Approximately 15% | Oral absorption efficiency |
| Metabolism | Via CYP3A4 enzyme | Liver processing of drug |