Dapoxetine 60mg: Dosage Guidelines and Administration Instructions

Dapoxetin > dapoxetine 60 mg tablets


Unfortunately, the efficacy and safety of dapoxetine (30 mg and 60 mg on-demand) has never been comprehensively studied in men with PE. Most data derived from clinical studies in men with PE are available.

Tên thương mại

This medicine can make you faint or make your blood pressure drop when you stand up. To decrease the chance of this happening take Dapotime with at least one full glass of water and do not take this medication in case you are dehydrated. In case of a history of documented or suspected orthostatic reaction, treatment with Generic Dapoxetine tablets should be avoided. Patients with underlying cardiovascular disease must not be administered dapoxetine tadalafil tablets this medicine as there is a risk of adverse cardiovascular outcomes from syncope. Dapoxetine HCl SideEffects © Clearsky Pharmacy ➢The other side effects occurring in 1% or more of the subjects in clinical trials were: Abdominal pain, Abdominal pain upper, Dyspepsia, Flatulence, Stomach discomfort, Abdominal distension, Dry mouth, Hyperhidrosis, Erectile dysfunction, Fatigue, Irritability and Blood pressure increased.

Brand Names

➢This is not a complete list of side effects. Dapotime Tablets © ClearskyPharmacy Contraindications Dapotime is contraindicated in patients with a hypersensitivity to Dapoxetine Hydrochloride or any other component of this medication. This medicine is also contraindicated in patients with significant pathological cardiac conditions. Dapotime (Generic Dapoxetine Hydrochloride tablets) is contraindicated for concomitant treatment with monoamine oxidase inhibitors (MAOIs), or within fourteen days of discontinuing treatment with an MAOI. Dapotime Tablets © ClearskyPharmacy Contraindications Generic Dapoxetine Hydrochloride (Dapotime Tablets) is contraindicated for concomitant treatment with thioridazine, or within 14 days of stopping treatment with Thioridazine. The objective of this study was to not only evaluate the efficacy and safety of dapoxetine when used at either 30 mg or 60 mg as compared with the placebo as an oral on-demand treatment in

Product Dosage Quantity + Bonus Price
Priligy Generic Dapoxetine60mg120 + 10 Pills341.26€ 325.01€
Priligy Generic Dapoxetine60mg30 + 6 Pills106.65€ 101.57€
Kamagra Oral Jelly100mg110 + 9 Sachets334.87€ 318.92€
Priligy Generic Dapoxetine60mg60 + 8 Pills183.06€ 174.34€
Cialis Soft Tabs20mg120 + 6 Pills248.64€ 236.80€
Viagra Generic25mg30 + 4 Pills47.97€ 45.69€
Priligy Generic Dapoxetine60mg180 + 10 Pills494.76€ 471.20€
Priligy Generic Dapoxetine60mg20 + 4 Pills77.31€ 73.63€
Priligy Generic Dapoxetine60mg90 + 10 Pills265.64€ 252.99€
Kamagra100mg120 + 6 Pills330.74€ 314.99€
Priligy Generic Dapoxetine60mg10 Pills47.63€ 45.36€

men with PE in routine clinical practice by performing a meta-analytic synthesis of studies, but also to assess whether there are differences in efficacy and safety for PE treatment using either 30 mg or 60 mg dapoxetine.

  • Overdose may present with serotonin syndrome: agitation, hyperthermia, tremor, and clonus.
  • Management is supportive; no specific antidote exists; seek immediate medical attention.
  • Dialysis is unlikely to remove dapoxetine effectively due to high protein binding.

The electronic and manual searches of PubMed, EMBASE and Cochrane Central Register of Controlled Trials (Cochrane Library) databases resulted in 106 references, of which 88 were clearly not relevant to our study.

Priligy dapoxetine

We conclude tadalafil dapoxetine that dapoxetine (particularly the 60 mg dosage) may be considered a safe and effective drug for patients with PE. Premature ejaculation (PE) is the most common male sexual dysfunction with a prevalence of between 20% and 40%1,2. Recently, the International Society for Sexual Medicine has proposed the following evidence-based definition: “PE is a male sexual dysfunction characterized by ejaculation that always or nearly always occurs prior to or within about 1 minute of vaginal penetration; inability to delay ejaculation on all or nearly all vaginal penetrations; and negative personal consequences, such as distress, bother, frustration, and/or the avoidance of sexual intimacy”3,4. In addition, PE affects numerous aspects of a man's life, including sexual confidence, interpersonal relationships and the sexual satisfaction of both partners5. The role of PE on the individual and the sexual relationship is very significant.

2.3 Pharmacokinetics

Thus, it is important to treat patients with PE in order to improve quality of life. At present, treatment of PE includes mainly psychotherapy, drug therapy and surgical treatment6. Drug therapy is not only likely to be the most receptive approach for patients, but it is also the most commonly used method. Selective serotonin reuptake inhibitors (SSRIs) have become the most widely used medicine in the world7. Dapoxetine hydrochloride, belonging to the class of SSRIs, was the first drug originally approved for the on-demand treatment of men with PE by seven European countries in 20088. Of the remaining 18 references, 11 were excluded after reading the full text.

User Feedback Aspect Average Rating (out of 5) Comments Notes
Effectiveness 4.2 Improved control over ejaculation Consistent results reported
Onset of Action 4.5 Usually within 1-2 hours Fast-acting
Side Effects 3.8 Mild nausea or dizziness occasional Generally well-tolerated
Overall Satisfaction 4.1 Positive experiences overall Widely used by satisfied users

After a quality validation, only seven studies9,10,11,12,13,14,15 were selected from the literature search.

What is Priligy

The recommended starting dose for all patients is 30 mg, taken as needed approximately one to three hours before sexual activity. ➢In case the effect of 30 mg is not sufficient and the side effects are acceptable, the dose may be increased to the maximum recommended dose of 60 mg. The maximum recommended dosing frequency is one dose every 24 hours. 24 hours must pass before taking your next dose. The dosage of Generic Dapoxetine tablets (Dapotime) is given below: Storage Instructions © ClearskyPharmacy Dapotime (Dapoxetine Hydrochloride Tablets) have to be stored at controlled room temperature i.e.

Chemical Names

Keep this as well as all other medicines away from children and pets. Warnings © Clearsky Pharmacy Dizziness,disturbance in attention, syncope, blurred vision and somnolence have been reported in patients administered Dapoxetine during clinical trials. Therefore, patients must be warned to avoid situations where injury could result, including driving or operating hazardous machinery. Combining alcohol with Dapotime may increase alcohol related neurocognitive effects and may also increase neurocardiogenic adverse events such as syncope, thereby increasing the risk of accidental injury; therefore, patients must be advised to avoid alcohol while taking Dapoxetine Hydrochloride tablets ( Dapotime ). Warnings © Clearsky Pharmacy Patientsshould be advised not to use Generic Dapoxetine tablets in combination with recreational drugs as they may lead to potentially serious reactions if combined with Dapotime. The flow chart of the evidence acquisition process is summarized in Figure 1 and the methodological quality of the included studies is reported in Figure 2.

Can I increase the dose of dapoxetine?

Dapotime is contraindicated for concomitant treatment with Serotonin reuptake inhibitors [selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs)] or other medicinal/herbal products with serotonergic effects or within 14 days of discontinuing treatment with these medicinal/herbal products. Dapotime is contraindicated for concomitant treatment with potent CYP3A4 inhibitors such as ketoconazole, itraconazole, ritonavir, saquinavir, telithromycin, nefazodone, nelfinavir, atazanavir, etc Generic Dapoxetine Hydrochloride Tablets are contraindicated in patients with moderate and severe hepatic impairment. Dapoxetine HCl SideEffects © Clearsky Pharmacy ➢Dapotime (Dapoxetine Hydrochloride Tablets) side effects occurring in 5% or more of patients are headache, dizziness, nausea, diarrhoea, insomnia and fatigue. ➢The other side effects occurring in 1% or more of the subjects in clinical trials were: Anxiety, Agitation, Restlessness, Insomnia, Abnormal dreams, Libido decreased, Somnolence, Disturbance in attention, Tremor, Paraesthesia, Vision blurred, Tinnitus, Flushing,Sinus congestion, Yawning, Diarrhoea, Vomiting, Constipation. Generic Dapoxetine Overdose ©Clearsky Pharmacy There were no unexpected adverse events in a clinical pharmacology study of Dapoxetine Hydrochloride with daily doses up to 240 mg (two 120 mg doses given 3 hours apart).

Chemical Formula

In general, symptoms of overdose with SSRIs include serotonin-mediated adverse reactions such as somnolence, gastrointestinal disturbances such as nausea and vomiting, tachycardia, tremor, agitation and dizziness. Generic Dapoxetine Overdose ©Clearsky Pharmacy In cases of overdose, standard supportive measures should be adopted as required. Due to high protein binding and large volume of distribution of Dapoxetine Hydrochloride, forced diuresis, dialysis, hemoperfusion and exchange transfusion are unlikely to be of benefit. No specific antidotes for Dapotime Tablets (Generic Dapoxetine Hydrochloride) are currently known. Generic Dapoxetine DuringPregnancy © Clearsky Pharmacy Dapoxetine Hydrochloride (Dapotime Tablets) has been classified by the FDA as Pregnancy Category C (AU TGA). Seven randomized controlled trials (RCTs) involving 8039 PE patients met the inclusion criteria.

  • Prescription only in most countries; requires medical evaluation before initiation.
  • A baseline assessment of blood pressure and cardiovascular risk is recommended.
  • Regular follow-up every 3-6 months to monitor efficacy and side effect profile.

Of these, 2478, 2932 and 2629 patients received 30 mg dapoxetine, 60 mg dapoxetine, or the placebo, respectively.

Efficacy Assessments

Dapotime (Generic Dapoxetine Hydrochloride) is not indicated for use by women. Generic Dapoxetine Tablets Formore details on Generic Dapoxetine Tablets click here © Clearsky Pharmacy Dapotime Tablets (Generic Dapoxetine Hydrochloride) by HAB Pharmaceuticals and Research Ltd. (Signature), India. Premature ejaculation (PE) is the most common male sexual dysfunction. Dapoxetine hydrochloride, belonging to a class of drugs known as selective serotonin reuptake inhibitors or, was the first drug originally approved for the on-demand treatment of men with PE.

Cite this article

We aimed to compare the intravaginal ejaculatory latency time (IELT), patient-reported global impression of change (PGIC) and adverse effect (AE) incidence associated dapoxetine sex with the use of dapoxetine (30 mg and 60 mg) versus placebo and evaluate the differences in administering 60 mg versus 30 mg as on-demand medical oral therapy for the treatment of PE via a literature review and meta-analysis. Relevant randomized controlled trials (RCTs) were identified from PubMed, EMBASE and Cochrane Central Register of Controlled Trials (Cochrane Library) databases. Ultimately, a total of seven RCTs with 8039 patients were included. Our meta-analysis demonstrated that dapoxetine (in the 30 mg and 60 mg subgroup) resulted in significantly higher IELT, PGIC and AE incidence relative to the placebo, with higher proportions observed for 60 mg versus 30 mg of dapoxetine administration. The most common AEs were mild and tolerable. The study included patients aged 18 years or older and the patients were randomized for dapoxetine 30 mg or dapoxetine 60 mg or placebo administration on-demand (1–3 hours prior to anticipated sexual activity).

  • Dapoxetine 60 mg is supplied in tablet form, easy to swallow with water.
  • Any sudden allergic reactions such as rash, swelling, or difficulty breathing require emergency care.
  • This medication is part of a treatment plan that may include counseling or therapy.
  • Dapoxetine is generally well-tolerated but requires medical evaluation before use.
  • Use cautiously if you have a history of fainting or low blood pressure.
  • The medication should not be used more than once within 24 hours.
  • Discuss any past incidents of mood changes or depression with your doctor.
  • Always confirm the authenticity of the medication before purchase to avoid counterfeit drugs.

The basic characteristics of the included studies are summarized in Table 1.

  • Alcohol consumption during dapoxetine use may increase sedation, dizziness, and fainting risk.
  • Patients should avoid driving or operating heavy machinery if they experience dizziness or somnolence.
  • Grapefruit juice may modestly increase dapoxetine exposure; limited clinical relevance.