Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

5.8 Hepatic Impairment

Do not eat grapefruit or drink grapefruit juice while you are using this medicine. Grapefruit and grapefruit juice may change the amount of this medicine that is absorbed in the body. The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine.

What to do in case of overdose

If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (tablets):For treatment of benign prostatic hyperplasia (daily use):Adults—5 milligrams (mg) as a single dose, no more than once a day, taken at the same time each day.Children—Use is not recommended.For treatment of erectile dysfunction (as needed):Adults—10 milligrams (mg) as a single dose, no more than once a day, taken 30 minutes before you think sexual activity may occur. Your doctor may adjust your dose as needed.Children—Use is not recommended.For treatment of erectile dysfunction (daily use):Adults—2.5 milligrams (mg) once a day, taken at the same time each day, without regard for the timing of sexual activity. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. It is important that you tell all of your doctors that you take tadalafil.

Product Dosage Quantity + Bonus Price
Cialis Generic20mg360 + 10 Pills427.34€ 406.99€
Cialis Original20mg64 + 4 Pills274.18€ 261.12€
Cialis Original20mg14 + 2 Pills95.75€ 91.19€
Cialis Professional40mg180 + 4 Pills618.23€ 588.79€
Cialis Professional20mg90 + 2 Pills241.49€ 229.99€
Cialis Professional20mg10 Pills48.29€ 45.99€
Cialis Soft Tabs20mg120 + 6 Pills248.64€ 236.80€
Cialis Professional20mg360 + 6 Pills807.03€ 768.60€
Cialis Professional40mg30 Pills148.94€ 141.85€
Cialis Soft Tabs20mg60 + 4 Pills159.37€ 151.78€
Cialis Generic10mg90 + 6 Pills146.17€ 139.21€
Cialis Generic10mg360 + 10 Pills388.49€ 369.99€
Cialis Professional40mg270 + 6 Pills898.37€ 855.59€
Cialis Generic20mg180 + 10 Pills254.09€ 241.99€
Cialis Super Active20mg120 + 16 Pills382.15€ 363.95€
Cialis Generic5mg360 + 10 Pills268.08€ 255.31€

If you need emergency medical care for a heart problem, it is important that your doctor knows when you last took tadalafil.

Comparing the Mechanism of Action

Your doctor may adjust your dose as needed.Children—Use is not recommended.For treatment of erectile dysfunction and benign prostatic hyperplasia (daily use):Adults—5 milligrams (mg) once a day, taken at the same time each day, without regard for the timing of sexual activity.Children—Use is not recommended.For treatment of pulmonary arterial hypertension:Adults—40 milligrams (mg) (two 20 mg tablets) taken once a day. Take both tablets at the same time each day. Your doctor may adjust your dose as needed.Children—Use and dose must be determined by your doctor. For treatment of benign prostatic hyperplasia (daily use):Adults—5 milligrams (mg) as a single dose, no more than once a day, taken at the same time each generic cialis soft 20mg day.Children—Use is not recommended. Adults—5 milligrams (mg) as a single dose, no more than once a day, taken at the same time each day.

Side effects and risks

For treatment of erectile dysfunction (as needed):Adults—10 milligrams (mg) as a single dose, no more than once a day, taken 30 minutes before you think sexual activity may occur. Your doctor may adjust your dose as needed.Children—Use is not recommended. Adults—10 milligrams (mg) as a single dose, no more than once a day, taken 30 minutes before you think sexual activity may occur. Your doctor may adjust your dose as needed. For treatment of erectile dysfunction (daily use):Adults—2.5 milligrams (mg) once a day, taken at the same time each day, without regard for the timing of sexual activity. If you will be taking this medicine for pulmonary arterial hypertension, it is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. Blood and urine tests may be needed to check for unwanted effects.

  • Cialis may be prescribed for pulmonary arterial hypertension under different dosing.
  • Use caution when driving or operating machinery after taking Cialis.
  • Sexual activity itself poses some risks for people with heart problems.
  • Report any side effects or unusual symptoms to your doctor promptly.
  • Follow dosing instructions precisely to minimize the risk of interactions.

If you take tadalafil for pulmonary arterial hypertension, do not take Cialis® or other PDE5 inhibitors, including sildenafil (Revatio® or Viagra®) or vardenafil (Levitra®).

17.9 Sexually Transmitted Disease

Also, do not stop taking this medicine without checking first with your doctor. This medicine comes with a patient information leaflet. Read it again each time you refill your prescription in case there is new information. Ask your doctor if you have any questions. You may take this medicine with or without food.

Could I take an 80-mg dose of Cialis?

Do not split, break, chew, or crush it. Chewable tablets: Chew the tablet completely before swallowing. When using this medicine for erectile dysfunction, the ability to have sexual activity may be improved for up to 36 hours after taking the tablet. Use only the brand of this medicine that your doctor prescribed. Different brands may not work the same way. If you take too much tadalafil or take it together with these medicines, the chance for side effects will be higher.

Side Effect Severity Recommended Action
Headache Mild to moderate Take analgesics if necessary
Flushing Mild Usually temporary
Dizziness Mild to moderate Avoid driving if dizzy
Priapism Severe, rare Seek immediate medical help
Vision changes Rare Discontinue & consult doctor

If you experience a prolonged erection for more than 4 hours or a painful erection for more than 6 hours, contact your doctor immediately. This condition may require prompt medical treatment to prevent serious and permanent damage to your penis. This medicine does not protect you against sexually transmitted diseases (including HIV or AIDS). Use protective measures and ask your doctor if you have any questions about this.

17.10 Recommended Administration

Children—Use and dose must be determined by your doctor. For treatment of benign prostatic hyperplasia (daily use): For oral dosage form (chewable tablet):For treatment of benign prostatic hyperplasia (daily use):Adults—5 milligrams (mg) once a day, taken at about the same time each day. Your doctor may adjust your dose as needed.Children—Use is not recommended.For treatment of erectile dysfunction (as needed):Adults—10 milligrams (mg) as a single dose, no more than once a day, taken 30 minutes before you think sexual activity may occur. Your doctor may adjust your dose as needed.Children—Use is not recommended.For treatment of erectile dysfunction and benign prostatic hyperplasia (daily use):Adults—5 milligrams (mg) once a day, taken at about the same time each day, without regard for the timing of sexual activity.Children—Use is not recommended. For treatment of benign prostatic hyperplasia (daily use):Adults—5 milligrams (mg) once a day, taken at about the same time each day. It is important to tell your doctor about any heart problems you have now or may have had in the past. This medicine can cause serious side effects in patients with heart problems. Do not use this medicine if you are also using riociguat (Adempas®) or a nitrate medicine, often used to treat angina (chest pain).

Proper Use

Adults—5 milligrams (mg) once a day, taken at about the same time each day. For treatment of erectile dysfunction and benign prostatic hyperplasia (daily use):Adults—5 milligrams (mg) once a day, taken at about the same time each day, without regard for the timing of sexual activity.Children—Use is not recommended. Adults—5 milligrams (mg) once a day, taken at about the same time each day, without regard for the timing of sexual activity. For treatment of benign prostatic hyperplasia (daily use): If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Some illegal ("street") drugs called "poppers" (such as amyl nitrate, butyl nitrate, or nitrite) also contain nitrates.

  • Missing doses or irregular use may reduce Cialis’s effectiveness.
  • It is crucial to understand potential drug interactions before starting therapy.
  • Keep a medication schedule to avoid accidental overdose or missed doses.
  • Regular follow-ups with your doctor can help optimize treatment outcomes.
  • Use Cialis responsibly to maintain good health and safety.

If you need to use a nitrate medicine, take it at least 48 hours after your last dose of tadalafil. Do not drink excessive amounts of alcohol (eg, 5 or more glasses of wine or 5 or more shots of whiskey) when taking tadalafil. When taken in excess, alcohol can increase your chances of getting a headache or dizziness, increase your heart rate, or lower your blood pressure.

17.8 Alcohol

Make sure you tell your doctor if you have any other medical problems, especially: Abnormal penis, including curved penis and birth defects of the penis (eg, angulation, cavernosal fibrosis, or Peyronie’s disease) or Sickle-cell anemia (blood disorder)—Use with caution. May increase risk of unwanted side effects (eg, prolonged erection of the penis). Crowded optic disc or low cup to disc ratio in the eye (an eye disorder) or Hyperlipidemia (high lipids or fats in the blood) or Non-arteritic anterior ischemic optic neuropathy or NAION (serious eye condition), history of or May increase risk for non–arteritic anterior ischemic optic neuropathy (NAION). Blood vessel problems (eg, aortic stenosis, idiopathic subaortic stenosis) or Heart attack (within the last 3 months) or Heart failure (within the last 6 months) or Retinitis pigmentosa (an inherited eye disorder) or Stroke (within the last 6 months)—Should not be used in patients with these conditions. Stomach ulcers—Use must be determined by your doctor.

Does tadalafil interact with foods or drinks?

Pulmonary veno-occlusive disease or PVOD (a type of lung disease)—Use with caution. Liver disease, mild or moderate—Use with caution. The effects may be increased because of slower removal of the medicine from the body. Use tadalafil exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. If you experience sudden loss of vision in one or both eyes, contact your doctor immediately.

Instructions Details Precautions
Dosage Timing Once per day, at same time each day Do not double doses
Food Interactions Take with or without food High-fat meals may delay absorption
Alcohol Consumption Limit alcohol intake Excess alcohol can increase side effects
Missed Dose Skip missed dose, do not double

Check with your doctor right away if you have a sudden decrease in hearing or loss of hearing, which may be accompanied by dizziness and ringing in the ears. Do not take other medicines unless they have been discussed with your doctor.

Medication Dosage Forms Onset Time Duration Price (approx.)
Cialis 20mg Tablets 30-60 minutes Up to 36 hours Moderate
Viagra 50mg Tablets 30-60 minutes 4-6 hours Moderate
Levitra 10mg Tablets 30 minutes 4-5 hours Slightly higher
Stendra 100mg Tablets 15-30 minutes 6 hours Higher

This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

12.1 Mechanism of Action

Adults—2.5 milligrams (mg) once a day, taken at the same time each day, without regard for the timing of sexual activity. For treatment of erectile dysfunction and benign prostatic hyperplasia (daily use):Adults—5 milligrams (mg) once a day, taken at the same time each day, without regard for the timing of sexual activity.Children—Use is not recommended. Adults—5 milligrams (mg) once a day, taken at the same time each day, without regard for the timing of sexual activity. For treatment of pulmonary arterial hypertension:Adults—40 milligrams (mg) (two 20 mg tablets) taken once a day. Adults—40 milligrams (mg) (two 20 mg tablets) taken once a day.